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Estimating tumor mutational burden from RNA-sequencing without a matched-normal sample

Detection of somatic mutations using patients sequencing data has many clinical applications, including the identification of cancer driver genes, detection of mutational signatures, and estimation of tumor mutational burden (TMB). We have previously developed a tool for detection of somatic mutatio...

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Detalles Bibliográficos
Autores principales:	Katzir, Rotem, Rudberg, Noam, Yizhak, Keren
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163107/ https://www.ncbi.nlm.nih.gov/pubmed/35654823 http://dx.doi.org/10.1038/s41467-022-30753-2

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