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Excessive branched-chain amino acid accumulation restricts mesenchymal stem cell-based therapy efficacy in myocardial infarction

Mesenchymal stem cells (MSCs) delivered into the post-ischemic heart milieu have a low survival and retention rate, thus restricting the cardioreparative efficacy of MSC-based therapy. Chronic ischemia results in metabolic reprogramming in the heart, but little is known about how these metabolic cha...

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Detalles Bibliográficos
Autores principales:	Zhang, Fuyang, Hu, Guangyu, Chen, Xiyao, Zhang, Ling, Guo, Lanyan, Li, Congye, Zhao, Hang, Cui, Zhe, Guo, Xiong, Sun, Fangfang, Song, Dandan, Yan, Wenjun, Xia, Yunlong, Wang, Shan, Fan, Miaomiao, Tao, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163108/ https://www.ncbi.nlm.nih.gov/pubmed/35654769 http://dx.doi.org/10.1038/s41392-022-00971-7

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