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Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes

Recognition of pathogen-or-damage-associated molecular patterns is critical to inflammation. However, most pathogen-or-damage-associated molecular patterns exist within intact microbes/cells and are typically part of non-diffusible, stable macromolecules that are not optimally immunostimulatory or a...

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Detalles Bibliográficos
Autores principales: Greene, Catherine J., Nguyen, Jenny A., Cheung, Samuel M., Arnold, Corey R., Balce, Dale R., Wang, Ya Ting, Soderholm, Adrian, McKenna, Neil, Aggarwal, Devin, Campden, Rhiannon I., Ewanchuk, Benjamin W., Virgin, Herbert W., Yates, Robin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163141/
https://www.ncbi.nlm.nih.gov/pubmed/35654768
http://dx.doi.org/10.1038/s41467-022-30654-4