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Comprehensive characterization of posttranscriptional impairment-related 3′-UTR mutations in 2413 whole genomes of cancer patients

The 3′ untranslated region (3′-UTR) is the vital element regulating gene expression, but most studies have focused on variations in RNA-binding proteins (RBPs), miRNAs, alternative polyadenylation (APA) and RNA modifications. To explore the posttranscriptional function of 3′-UTR somatic mutations in...

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Detalles Bibliográficos
Autores principales: Wei, Wenqing, Gao, Wenyan, Li, Qinglan, Liu, Yuhao, Chen, Hongyan, Cui, Yongping, Sun, Zhongsheng, Liu, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163142/
https://www.ncbi.nlm.nih.gov/pubmed/35654793
http://dx.doi.org/10.1038/s41525-022-00305-0