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Comprehensive characterization of posttranscriptional impairment-related 3′-UTR mutations in 2413 whole genomes of cancer patients
The 3′ untranslated region (3′-UTR) is the vital element regulating gene expression, but most studies have focused on variations in RNA-binding proteins (RBPs), miRNAs, alternative polyadenylation (APA) and RNA modifications. To explore the posttranscriptional function of 3′-UTR somatic mutations in...
Autores principales: | Wei, Wenqing, Gao, Wenyan, Li, Qinglan, Liu, Yuhao, Chen, Hongyan, Cui, Yongping, Sun, Zhongsheng, Liu, Zhihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163142/ https://www.ncbi.nlm.nih.gov/pubmed/35654793 http://dx.doi.org/10.1038/s41525-022-00305-0 |
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