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Measurement of circulating CD21(−)CD27(−) B lymphocytes in SLE patients is associated with disease activity independently of conventional serological biomarkers

Determining disease activity in systemic lupus erythematosus (SLE) patients is challenging and limited by the lack of reliable biomarkers. Abnormally activated B cells play a key role in the pathogenesis of SLE, but their measure in clinical practice is currently not recommended. Here, we studied pe...

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Detalles Bibliográficos
Autores principales: Horisberger, Alice, Humbel, Morgane, Fluder, Natalia, Bellanger, Florence, Fenwick, Craig, Ribi, Camillo, Comte, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163192/
https://www.ncbi.nlm.nih.gov/pubmed/35654865
http://dx.doi.org/10.1038/s41598-022-12775-4

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