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Measurement of circulating CD21(−)CD27(−) B lymphocytes in SLE patients is associated with disease activity independently of conventional serological biomarkers
Determining disease activity in systemic lupus erythematosus (SLE) patients is challenging and limited by the lack of reliable biomarkers. Abnormally activated B cells play a key role in the pathogenesis of SLE, but their measure in clinical practice is currently not recommended. Here, we studied pe...
Autores principales: | Horisberger, Alice, Humbel, Morgane, Fluder, Natalia, Bellanger, Florence, Fenwick, Craig, Ribi, Camillo, Comte, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163192/ https://www.ncbi.nlm.nih.gov/pubmed/35654865 http://dx.doi.org/10.1038/s41598-022-12775-4 |
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