Immunization with CSP and a RIG-I Agonist is Effective in Inducing a Functional and Protective Humoral Response Against Plasmodium

Malaria is a major public health concern, as a highly effective human vaccine remains elusive. The efficacy of a subunit vaccine targeting the most abundant protein of the sporozoite surface, the circumsporozoite protein (CSP) has been hindered by difficulties in generating an effective humoral resp...

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Detalles Bibliográficos
Autores principales: Teixeira, Ana Rafaela, Pérez-Cabezas, Begoña, Costa, David M., Sá, Mónica, Golba, Sylvain, Sefiane-Djemaoune, Hélèna, Ribeiro, Joana, Kaneko, Izumi, Iwanaga, Shiroh, Yuda, Masao, Tsuji, Moriya, Boscardin, Silvia Beatriz, Amino, Rogerio, Cordeiro-da-Silva, Anabela, Tavares, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163323/
https://www.ncbi.nlm.nih.gov/pubmed/35669785
http://dx.doi.org/10.3389/fimmu.2022.868305

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