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Repositioning of the Angiotensin II Receptor Antagonist Candesartan as an Anti-Inflammatory Agent With NLRP3 Inflammasome Inhibitory Activity

Aberrant activation of the NLRP3 inflammasome promotes the pathogenesis of many inflammatory diseases. The development of the NLRP3 inflammasome inhibitors from existing drugs for new therapeutic purposes is becoming more important. Candesartan is an angiotensin II receptor antagonist widely used as...

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Detalles Bibliográficos
Autores principales:	Lin, Wen-Yu, Li, Lan-Hui, Hsiao, Ya-Yun, Wong, Wei-Ting, Chiu, Hsiao-Wen, Hsu, Hsien-Ta, Peng, Yi-Jen, Ho, Chen-Lung, Chernikov, Oleg V., Cheng, Shu-Meng, Yang, Shih-Ping, Hua, Kuo-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163344/ https://www.ncbi.nlm.nih.gov/pubmed/35669789 http://dx.doi.org/10.3389/fimmu.2022.870627

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