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The Alteration of T-Cell Heterogeneity and PD-L1 Colocalization During dMMR Colorectal Cancer Progression Defined by Multiplex Immunohistochemistry

BACKGROUND: Immune checkpoint inhibitors (ICIs) are quickly becoming key instruments in the treatment of mismatch repair-deficient (dMMR) colorectal cancers (CRCs). Despite their clinical value, ICIs have several limitations associated with their use. Only approximately 15% of all CRCs have a dMMR s...

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Detalles Bibliográficos
Autores principales:	Yan, Hongkai, Li, Yaqi, Wang, Xiaoyu, Qian, Juanjuan, Xu, Midie, Peng, Junjie, Huang, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163547/ https://www.ncbi.nlm.nih.gov/pubmed/35669431 http://dx.doi.org/10.3389/fonc.2022.867658

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