Differential Degradation of TRA2A and PYCR2 Mediated by Ubiquitin E3 Ligase E4B

E4B belongs to the U-box E3 ligase family and functions as either an E3 or an E4 enzyme in protein ubiquitination. Transformer2A (TRA2A) and Pyrroline-5-carboxylate reductase 2 (PYCR2) are related to cancer development and are overexpressed in many cancer cells. The degradation of TRA2A and PYCR2 me...

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Detalles Bibliográficos
Autores principales: Lu, Yao, Jiang, Bo, Peng, Kangli, Li, Shasha, Liu, Xiangnan, Wang, Bufan, Chen, Yuntian, Wang, Tiepeng, Zhao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163560/
https://www.ncbi.nlm.nih.gov/pubmed/35669517
http://dx.doi.org/10.3389/fcell.2022.833396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163560/
https://www.ncbi.nlm.nih.gov/pubmed/35669517
http://dx.doi.org/10.3389/fcell.2022.833396

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