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COT: an efficient and accurate method for detecting marker genes among many subtypes
MOTIVATION: Ideally, a molecularly distinct subtype would be composed of molecular features that are expressed uniquely in the subtype of interest but in no others—so-called marker genes (MGs). MG plays a critical role in the characterization, classification or deconvolution of tissue or cell subtyp...
Autores principales: | Lu, Yingzhou, Wu, Chiung-Ting, Parker, Sarah J, Cheng, Zuolin, Saylor, Georgia, Van Eyk, Jennifer E, Yu, Guoqiang, Clarke, Robert, Herrington, David M, Wang, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163574/ https://www.ncbi.nlm.nih.gov/pubmed/35673616 http://dx.doi.org/10.1093/bioadv/vbac037 |
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