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Lactate Dehydrogenase B Is Required for Pancreatic Cancer Cell Immortalization Through Activation of Telomerase Activity

Telomerase activity is elevated in most cancer cells and is required for telomere length maintenance and immortalization of cancer cells. Glucose metabolic reprogramming is a hallmark of cancer and accompanied with increased expression of key metabolic enzymes. Whether these enzymes influence telome...

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Detalles Bibliográficos
Autores principales:	Wang, Ruiguan, Li, Jiangbo, Zhang, Changjian, Guan, Xin, Qin, Boyu, Jin, Rui, Qin, Lingmei, Xu, Shanrong, Zhang, Xiaona, Liu, Rong, Ye, Qinong, Cheng, Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163669/ https://www.ncbi.nlm.nih.gov/pubmed/35669414 http://dx.doi.org/10.3389/fonc.2022.821620

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