Treatment With LAU-7b Complements CFTR Modulator Therapy by Improving Lung Physiology and Normalizing Lipid Imbalance Associated With CF Lung Disease

Cystic fibrosis (CF) is the most common autosomal recessive genetic disease in Caucasians, affecting more than 100,000 individuals worldwide. It is caused by pathogenic variants in the gene encoding CFTR, an anion channel at the plasma membrane of epithelial and other cells. Many CF pathogenic varia...

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Detalles Bibliográficos
Autores principales: Centorame, Amanda, Dumut, Daciana Catalina, Youssef, Mina, Ondra, Martin, Kianicka, Irenej, Shah, Juhi, Paun, Radu Alexandru, Ozdian, Tomas, Hanrahan, John W., Gusev, Ekaterina, Petrof, Basil, Hajduch, Marian, Pislariu, Radu, De Sanctis, Juan Bautista, Radzioch, Danuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163687/
https://www.ncbi.nlm.nih.gov/pubmed/35668939
http://dx.doi.org/10.3389/fphar.2022.876842

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