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The long β2,3-sheets encoded by redundant sequences play an integral role in the channel function of P2X7 receptors
P2X receptors are a class of nonselective cation channels widely distributed in the immune and nervous systems, and their dysfunction is a significant cause of tumors, inflammation, leukemia, and immune diseases. P2X7 is a unique member of the P2X receptor family with many properties that differ fro...
Autores principales: | Ma, Xue-Fei, Wang, Ting-Ting, Wang, Wen-Hui, Guan, Li, Guo, Chang-Run, Li, Xing-Hua, Lei, Yun-Tao, Fan, Ying-Zhe, Yang, Xiao-Na, Hattori, Motoyuki, Nureki, Osamu, Zhu, Michael X., Yu, Ye, Tian, Yun, Wang, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163701/ https://www.ncbi.nlm.nih.gov/pubmed/35504351 http://dx.doi.org/10.1016/j.jbc.2022.102002 |
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