Add-On MEmaNtine to Dopamine Antagonism to Improve Negative Symptoms at First Psychosis- the AMEND Trial Protocol

BACKGROUND: Antipsychotic drugs are primarily efficacious in treating positive symptoms by blocking the dopamine D2 receptor, but they fail to substantially improve negative symptoms and cognitive deficits. The limited efficacy may be attributed to the fact that the pathophysiology of psychosis invo...

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Detalles Bibliográficos
Autores principales: Sandström, Katharina O., Baltzersen, Olga B., Marsman, Anouk, Lemvigh, Cecilie K., Boer, Vincent O., Bojesen, Kirsten B., Nielsen, Mette Ø., Lundell, Henrik, Sulaiman, Daban K., Sørensen, Mikkel E., Fagerlund, Birgitte, Lahti, Adrienne C., Syeda, Warda T., Pantelis, Christos, Petersen, Esben T., Glenthøj, Birte Y., Siebner, Hartwig R., Ebdrup, Bjørn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163784/
https://www.ncbi.nlm.nih.gov/pubmed/35669271
http://dx.doi.org/10.3389/fpsyt.2022.889572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163784/
https://www.ncbi.nlm.nih.gov/pubmed/35669271
http://dx.doi.org/10.3389/fpsyt.2022.889572

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