Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art

Lipid tracing studies are a key method to gain a better understanding of the complex metabolic network lipids are involved in. In recent years, alkyne lipid tracers and mass spectrometry have been developed as powerful tools for such studies. This study aims to review the present standing of the und...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuerschner, Lars, Thiele, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163959/
https://www.ncbi.nlm.nih.gov/pubmed/35669564
http://dx.doi.org/10.3389/fmolb.2022.880559
_version_ 1784720030303256576
author Kuerschner, Lars
Thiele, Christoph
author_facet Kuerschner, Lars
Thiele, Christoph
author_sort Kuerschner, Lars
collection PubMed
description Lipid tracing studies are a key method to gain a better understanding of the complex metabolic network lipids are involved in. In recent years, alkyne lipid tracers and mass spectrometry have been developed as powerful tools for such studies. This study aims to review the present standing of the underlying technique, highlight major findings the strategy allowed for, summarize its advantages, and discuss some limitations. In addition, an outlook on future developments is given.
format Online
Article
Text
id pubmed-9163959
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-91639592022-06-05 Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art Kuerschner, Lars Thiele, Christoph Front Mol Biosci Molecular Biosciences Lipid tracing studies are a key method to gain a better understanding of the complex metabolic network lipids are involved in. In recent years, alkyne lipid tracers and mass spectrometry have been developed as powerful tools for such studies. This study aims to review the present standing of the underlying technique, highlight major findings the strategy allowed for, summarize its advantages, and discuss some limitations. In addition, an outlook on future developments is given. Frontiers Media S.A. 2022-05-20 /pmc/articles/PMC9163959/ /pubmed/35669564 http://dx.doi.org/10.3389/fmolb.2022.880559 Text en Copyright © 2022 Kuerschner and Thiele. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Molecular Biosciences
Kuerschner, Lars
Thiele, Christoph
Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art
title Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art
title_full Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art
title_fullStr Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art
title_full_unstemmed Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art
title_short Tracing Lipid Metabolism by Alkyne Lipids and Mass Spectrometry: The State of the Art
title_sort tracing lipid metabolism by alkyne lipids and mass spectrometry: the state of the art
topic Molecular Biosciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163959/
https://www.ncbi.nlm.nih.gov/pubmed/35669564
http://dx.doi.org/10.3389/fmolb.2022.880559
work_keys_str_mv AT kuerschnerlars tracinglipidmetabolismbyalkynelipidsandmassspectrometrythestateoftheart
AT thielechristoph tracinglipidmetabolismbyalkynelipidsandmassspectrometrythestateoftheart

Ejemplares similares