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Tyrosine catabolites influence SKN-1 signaling in a model of Type I Tyrosinemia

Hereditary Tyrosinemia Type 1 (HT1) is a rare genetic disease that results from mutations of the tyrosine catabolism enzyme fumarylacetoacetate hydrolase (FAH) for which there is currently no cure. HT1 is successfully modeled in the nematode C. elegans , via mutations in the fumarylacetoacetate hydr...

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Detalles Bibliográficos
Autores principales:	Siddiqi, Talha F, Frankino, Phillip A, Dillin, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Caltech Library 2022
Materias:	New Finding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163963/ https://www.ncbi.nlm.nih.gov/pubmed/35668715 http://dx.doi.org/10.17912/micropub.biology.000577

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