Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans

Not much is known about FAM136A, a human gene that may be involved in Meniere’s disease and is conserved throughout animals. To understand the function of famh-136 , the Caenorhabditis elegans ortholog of FAM136A, loss of function alleles of the gene were generated. We find that loss of famh-136 fun...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Chieh-Hsiang, Park, Heenam, Sternberg, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163966/
https://www.ncbi.nlm.nih.gov/pubmed/35668716
http://dx.doi.org/10.17912/micropub.biology.000553
Descripción
Sumario:Not much is known about FAM136A, a human gene that may be involved in Meniere’s disease and is conserved throughout animals. To understand the function of famh-136 , the Caenorhabditis elegans ortholog of FAM136A, loss of function alleles of the gene were generated. We find that loss of famh-136 function results in minor but significant changes to the locomotion and behavior.

Ejemplares similares