Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans

Not much is known about FAM136A, a human gene that may be involved in Meniere’s disease and is conserved throughout animals. To understand the function of famh-136 , the Caenorhabditis elegans ortholog of FAM136A, loss of function alleles of the gene were generated. We find that loss of famh-136 fun...

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Detalles Bibliográficos
Autores principales: Tan, Chieh-Hsiang, Park, Heenam, Sternberg, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163966/
https://www.ncbi.nlm.nih.gov/pubmed/35668716
http://dx.doi.org/10.17912/micropub.biology.000553
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author Tan, Chieh-Hsiang
Park, Heenam
Sternberg, Paul W.
author_facet Tan, Chieh-Hsiang
Park, Heenam
Sternberg, Paul W.
author_sort Tan, Chieh-Hsiang
collection PubMed
description Not much is known about FAM136A, a human gene that may be involved in Meniere’s disease and is conserved throughout animals. To understand the function of famh-136 , the Caenorhabditis elegans ortholog of FAM136A, loss of function alleles of the gene were generated. We find that loss of famh-136 function results in minor but significant changes to the locomotion and behavior.
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spelling pubmed-91639662022-06-05 Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans Tan, Chieh-Hsiang Park, Heenam Sternberg, Paul W. MicroPubl Biol New Finding Not much is known about FAM136A, a human gene that may be involved in Meniere’s disease and is conserved throughout animals. To understand the function of famh-136 , the Caenorhabditis elegans ortholog of FAM136A, loss of function alleles of the gene were generated. We find that loss of famh-136 function results in minor but significant changes to the locomotion and behavior. Caltech Library 2022-06-02 /pmc/articles/PMC9163966/ /pubmed/35668716 http://dx.doi.org/10.17912/micropub.biology.000553 Text en Copyright: © 2022 by the authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle New Finding
Tan, Chieh-Hsiang
Park, Heenam
Sternberg, Paul W.
Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans
title Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans
title_full Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans
title_fullStr Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans
title_full_unstemmed Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans
title_short Loss of famh-136/ FAM136A results in minor locomotion and behavioral changes in Caenorhabditis elegans
title_sort loss of famh-136/ fam136a results in minor locomotion and behavioral changes in caenorhabditis elegans
topic New Finding
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9163966/
https://www.ncbi.nlm.nih.gov/pubmed/35668716
http://dx.doi.org/10.17912/micropub.biology.000553
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AT sternbergpaulw lossoffamh136fam136aresultsinminorlocomotionandbehavioralchangesincaenorhabditiselegans

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