Investigating the Link between Alpha-1 Antitrypsin and Human Neutrophil Elastase in Bronchoalveolar Lavage Fluid of COVID-19 Patients

Neutrophils play a pathogenic role in COVID-19 by releasing Neutrophils Extracellular Traps (NETs) or human neutrophil elastase (HNE). Given that HNE is inhibited by α1-antitrypsin (AAT), we aimed to assess the content of HNE, α1-antitrypsin (AAT) and HNE–AAT complexes (the AAT/HNE balance) in 33 br...

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Detalles Bibliográficos
Autores principales: D’Amato, Maura, Vertui, Valentina, Pandolfi, Laura, Bozzini, Sara, Fossali, Tommaso, Colombo, Riccardo, Aliberti, Anna, Fumagalli, Marco, Iadarola, Paolo, Didò, Camilla, Viglio, Simona, Meloni, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164061/
https://www.ncbi.nlm.nih.gov/pubmed/35678672
http://dx.doi.org/10.3390/cimb44050143

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