Cargando…

Modeling Nonischemic Genetic Cardiomyopathies Using Induced Pluripotent Stem Cells

PURPOSE OF REVIEW: The advent of induced pluripotent stem cells (iPSC) has paved the way for new in vitro models of human cardiomyopathy. Herein, we will review existing models of disease as well as strengths and limitations of the system. RECENT FINDINGS: Preclinical studies have now demonstrated t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khedro, Tarek, Duran, Jason M., Adler, Eric D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Regenerative Medicine (SM Wu, Section Editor)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164178/ https://www.ncbi.nlm.nih.gov/pubmed/35657495 http://dx.doi.org/10.1007/s11886-022-01683-8

Ejemplares similares

Modeling Cardiac SARS-CoV-2 Infection with Human Pluripotent Stem Cells
por: Rockwood, Sarah J., et al.
Publicado: (2022)

Cardiac Cell Therapy with Pluripotent Stem Cell-Derived Cardiomyocytes: What Has Been Done and What Remains to Do?
por: Selvakumar, Dinesh, et al.
Publicado: (2022)

Model Systems for Addressing Mechanism of Arrhythmogenesis in Cardiac Repair
por: Zhang, Xiao-Dong, et al.
Publicado: (2021)

Calcific Aortic Valve Disease: a Developmental Biology Perspective
por: Dutta, Punashi, et al.
Publicado: (2018)

Four Dimensions of the Cardiac Myocyte Epigenome: from Fetal to Adult Heart
por: Rommel, Carolin, et al.
Publicado: (2020)

Role of Mononuclear Cardiomyocytes in Cardiac Turnover and Regeneration
por: Becker, Cora, et al.
Publicado: (2020)

A Change of Heart: Human Cardiac Tissue Engineering as a Platform for Drug Development
por: Bremner, Samantha B., et al.
Publicado: (2022)

Recent Advances in Single-Cell Profiling and Multispecific Therapeutics: Paving the Way for a New Era of Precision Medicine Targeting Cardiac Fibroblasts
por: Shi, Sally Yu, et al.
Publicado: (2021)

3D Printing Approaches to Engineer Cardiac Tissue
por: Lu, Ting-Yu, et al.
Publicado: (2023)

The Role of Innate Immune Cells in Cardiac Injury and Repair: A Metabolic Perspective
por: Banerjee, Durba, et al.
Publicado: (2023)

Formation of the Heart: Defining Cardiomyocyte Progenitors at Single-Cell Resolution
por: Tyser, Richard C. V.
Publicado: (2023)

InterLINCing Chromatin Organization and Mechanobiology in Laminopathies
por: Shah, Parisha P., et al.
Publicado: (2023)

Induced Pluripotent Stem Cells Restore Function in a Human Cell Loss Model of Open-Angle Glaucoma
por: Abu-Hassan, Diala W, et al.
Publicado: (2015)

Pluripotent stem cell‐derived retinal organoids for disease modeling and development of therapies
por: Kruczek, Kamil, et al.
Publicado: (2020)

Enhanced Function of Induced Pluripotent Stem Cell‐Derived Endothelial Cells Through ESM1 Signaling
por: Vilà‐González, Marta, et al.
Publicado: (2018)

Human iPS Cell-Derived Cardiac Tissue Sheets: a Platform for Cardiac Regeneration
por: Masumoto, Hidetoshi, et al.
Publicado: (2016)

Concise Review: Reduction of Adverse Cardiac Scarring Facilitates Pluripotent Stem Cell‐Based Therapy for Myocardial Infarction
por: Liang, Jialiang, et al.
Publicado: (2019)

Biventricular thrombi of nonischemic cardiomyopathy
por: Adnan, Mohammed Muqeet, et al.
Publicado: (2014)

Follistatin‐Like 3 Enhances the Function of Endothelial Cells Derived from Pluripotent Stem Cells by Facilitating β‐Catenin Nuclear Translocation Through Inhibition of Glycogen Synthase Kinase‐3β Activity
por: Kelaini, Sophia, et al.
Publicado: (2018)

High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling
por: Manstein, Felix, et al.
Publicado: (2021)

Coadministration of endothelial and smooth muscle cells derived from human induced pluripotent stem cells as a therapy for critical limb ischemia
por: Park, Jin Ju, et al.
Publicado: (2020)

Sibutramine-Induced Nonischemic Cardiomyopathy
por: Shah, Meet S, et al.
Publicado: (2022)

Optimized serial expansion of human induced pluripotent stem cells using low‐density inoculation to generate clinically relevant quantities in vertical‐wheel bioreactors
por: Borys, Breanna S., et al.
Publicado: (2020)

TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells
por: Osnato, Anna, et al.
Publicado: (2021)

Tumor-Free Transplantation of Patient-Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration
por: El Khatib, Moustafa M., et al.
Publicado: (2016)

HIF-2α Suppresses p53 to Enhance the Stemness and Regenerative Potential of Human Embryonic Stem Cells
por: Das, Bikul, et al.
Publicado: (2012)

Functional Maturation of Induced Pluripotent Stem Cell Hepatocytes in Extracellular Matrix—A Comparative Analysis of Bioartificial Liver Microenvironments
por: Wang, Bo, et al.
Publicado: (2016)

Autophagy Enhances Longevity of Induced Pluripotent Stem Cell-Derived Endothelium via mTOR-Independent ULK1 Kinase
por: Hekman, Katherine E, et al.
Publicado: (2022)

Allogeneic adipose‐derived stem cells promote ischemic muscle repair by inducing M2 macrophage polarization via the HIF‐1α/IL‐10 pathway
por: Liu, Junchao, et al.
Publicado: (2020)

Derivation of trophoblast stem cells from naïve human pluripotent stem cells
por: Dong, Chen, et al.
Publicado: (2020)

Stem Cells and Cartilage Development: Complexities of a Simple Tissue
por: Hollander, Anthony P, et al.
Publicado: (2010)

Allogeneic Periodontal Ligament Stem Cell Therapy for Periodontitis in Swine
por: Ding, Gang, et al.
Publicado: (2010)

Application of Tonsil‐Derived Mesenchymal Stem Cells in Tissue Regeneration: Concise Review
por: Oh, Se‐Young, et al.
Publicado: (2019)

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning
por: Morgani, Sophie M, et al.
Publicado: (2018)

Inhibition of T Cell Protein Tyrosine Phosphatase Enhances Interleukin-18-Dependent Hematopoietic Stem Cell Expansion
por: Bourdeau, Annie, et al.
Publicado: (2013)

Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation
por: Tassoni, Alessia, et al.
Publicado: (2015)

In Utero Transplantation of Expanded Autologous Amniotic Fluid Stem Cells Results in Long‐Term Hematopoietic Engraftment
por: Loukogeorgakis, Stavros P., et al.
Publicado: (2019)

Fisetin Attenuates Cellular Senescence Accumulation During Culture Expansion of Human Adipose-Derived Stem Cells
por: Mullen, Michael, et al.
Publicado: (2023)

Implantation of the clinical‐grade human neural stem cell line, CTX0E03, rescues the behavioral and pathological deficits in the quinolinic acid‐lesioned rodent model of Huntington's disease
por: Yoon, Yongwoo, et al.
Publicado: (2020)

Neuroprotective Effects of Human Mesenchymal Stem Cells and Platelet‐Derived Growth Factor on Human Retinal Ganglion Cells
por: Osborne, Andrew, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_98sgct2lt6ldbiusv0q605khgd