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Systematic evaluation of parameters in RNA bisulfite sequencing data generation and analysis

The presence of 5-methylcytosine (m(5)C) in RNA molecules has been known for decades and its importance in regulating RNA metabolism has gradually become appreciated. Despite recent advances made in the functional and mechanistic understanding of RNA m(5)C modifications, the detection and quantifica...

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Detalles Bibliográficos
Autores principales:	Johnson, Zachary, Xu, Xiguang, Pacholec, Christina, Xie, Hehuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	High Throughput Sequencing Methods
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164272/ https://www.ncbi.nlm.nih.gov/pubmed/35669236 http://dx.doi.org/10.1093/nargab/lqac045

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