New Era of Mapping and Understanding Common Fragile Sites: An Updated Review on Origin of Chromosome Fragility

Common fragile sites (CFSs) are specific genomic loci prone to forming gaps or breakages upon replication perturbation, which correlate well with chromosomal rearrangement and copy number variation. CFSs have been actively studied due to their important pathophysiological relevance in different dise...

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Detalles Bibliográficos
Autores principales: Ji, Fang, Zhu, Xinli, Liao, Hongwei, Ouyang, Liujian, Huang, Yingfei, Syeda, Madiha Zahra, Ying, Songmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164283/
https://www.ncbi.nlm.nih.gov/pubmed/35669181
http://dx.doi.org/10.3389/fgene.2022.906957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164283/
https://www.ncbi.nlm.nih.gov/pubmed/35669181
http://dx.doi.org/10.3389/fgene.2022.906957

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