Cargando…

New Era of Mapping and Understanding Common Fragile Sites: An Updated Review on Origin of Chromosome Fragility

Common fragile sites (CFSs) are specific genomic loci prone to forming gaps or breakages upon replication perturbation, which correlate well with chromosomal rearrangement and copy number variation. CFSs have been actively studied due to their important pathophysiological relevance in different dise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Fang, Zhu, Xinli, Liao, Hongwei, Ouyang, Liujian, Huang, Yingfei, Syeda, Madiha Zahra, Ying, Songmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164283/ https://www.ncbi.nlm.nih.gov/pubmed/35669181 http://dx.doi.org/10.3389/fgene.2022.906957

Ejemplares similares

Transcription-Replication Collisions and Chromosome Fragility
por: Wu, Wei, et al.
Publicado: (2021)

Fragile sites, chromosomal lesions, tandem repeats, and disease
por: Mirceta, Mila, et al.
Publicado: (2022)

Editorial: Chromosomal fragile sites, genome instability and human diseases
por: Hu, Qing, et al.
Publicado: (2023)

Common Threads: Aphidicolin-Inducible and Folate-Sensitive Fragile Sites in the Human Genome
por: Lokanga, Rachel Adihe, et al.
Publicado: (2021)

Cardiovascular Problems in the Fragile X Premutation
por: Tassanakijpanich, Nattaporn, et al.
Publicado: (2020)

Psychosis and Catatonia in Fragile X Syndrome
por: Keshtkarjahromi, Mitra, et al.
Publicado: (2021)

Common Chromosomal Fragile Sites—Conserved Failure Stories
por: Voutsinos, Vasileios, et al.
Publicado: (2018)

Large Intronic Deletion of the Fragile Site Gene PRKN Dramatically Lowers Its Fragility Without Impacting Gene Expression
por: Munk, Sebastian H. N., et al.
Publicado: (2021)

Timing of Expansion of Fragile X Premutation Alleles During Intergenerational Transmission in a Mouse Model of the Fragile X-Related Disorders
por: Zhao, Xiao-Nan, et al.
Publicado: (2018)

Non-canonical DNA/RNA structures associated with the pathogenesis of Fragile X-associated tremor/ataxia syndrome and Fragile X syndrome
por: Yousuf, Aadil, et al.
Publicado: (2022)

Zebrafish Chromosome 14 Gene Differential Expression in the fmr1(hu2787) Model of Fragile X Syndrome
por: Barthelson, Karissa, et al.
Publicado: (2021)

Fragility Fractures in Orthopaedics: An Update
por: Hou, Zhiyong, et al.
Publicado: (2017)

The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome
por: Kumari, Daman, et al.
Publicado: (2009)

Common Chromosomal Fragile Site Gene WWOX in Metabolic Disorders and Tumors
por: Li, Juan, et al.
Publicado: (2014)

De Novo Large Deletion Leading to Fragile X Syndrome
por: Jiraanont, Poonnada, et al.
Publicado: (2022)

The Cyclically Seasonal Drosophila subobscura Inversion O(7) Originated From Fragile Genomic Sites and Relocated Immunity and Metabolic Genes
por: Karageorgiou, Charikleia, et al.
Publicado: (2020)

A Single Common Assay for Robust and Rapid Fragile X Mental Retardation Syndrome Screening From Dried Blood Spots
por: Tan, Vivienne J., et al.
Publicado: (2018)

Identification of common fragile sites in chromosomes of 2 species of bat (Chiroptera, Mammalia)
por: Morielle-Versute, E, et al.
Publicado: (1994)

Common fragile sites: protection and repair
por: Li, Shibo, et al.
Publicado: (2020)

Updating the mechanisms of common fragile site instability: how to reconcile the different views?
por: Le Tallec, Benoît, et al.
Publicado: (2014)

DNA Instability at Chromosomal Fragile Sites in Cancer
por: Dillon, Laura W, et al.
Publicado: (2010)

Fragile
por: CERN Press Office. Geneva
Publicado: (1975)

Fragile Genomic Sites Are Associated with Origins of Replication
por: Di Rienzi, Sara C., et al.
Publicado: (2009)

The role of AGG interruptions in fragile X repeat expansions: a twenty-year perspective
por: Latham, Gary J., et al.
Publicado: (2014)

Repeat-mediated epigenetic dysregulation of the FMR1 gene in the fragile X-related disorders
por: Usdin, Karen, et al.
Publicado: (2015)

Fragile X-Associated Tremor/Ataxia Syndrome: Unmet Needs and a Path for the Future
por: Hall, Deborah A., et al.
Publicado: (2018)

Non-coding RNA in Fragile X Syndrome and Converging Mechanisms Shared by Related Disorders
por: Zhou, Yafang, et al.
Publicado: (2019)

Fragile X Associated Primary Ovarian Insufficiency (FXPOI): Case Report and Literature Review
por: Fink, Dorothy A., et al.
Publicado: (2018)

PSIS With Phenotypic Features of Prader Willi and Fragile X Syndrome
por: Ali, Syeda Fatima, et al.
Publicado: (2021)

Common fragile sites are characterized by histone hypoacetylation
por: Jiang, Yanwen, et al.
Publicado: (2009)

Advances in understanding the molecular basis of skin fragility
por: Has, Cristina
Publicado: (2018)

Is mammalian chromosomal evolution driven by regions of genome fragility?
por: Ruiz-Herrera, Aurora, et al.
Publicado: (2006)

Fragile site X chromosomes in mentally retarded boys.
por: Moon, H. R., et al.
Publicado: (1993)

Repeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disorders
por: Usdin, Karen, et al.
Publicado: (2014)

Fragile X Syndrome in a Female With Homozygous Full-Mutation Alleles of the FMR1 Gene
por: Vafaeie, Farzane, et al.
Publicado: (2021)

Fragile X syndrome and fragile X-associated disorders
por: Rajaratnam, Akash, et al.
Publicado: (2017)

How Fragile Are the Results of a Trial? The Fragility Index
por: Dettori, Joseph R., et al.
Publicado: (2020)

Fragility index and fragility quotient in randomized clinical trials
por: Garcia, Marcos Vinicius Fernandes, et al.
Publicado: (2023)

Dysregulated nitric oxide signaling as a candidate mechanism of fragile X syndrome and other neuropsychiatric disorders
por: Colvin, Steven M., et al.
Publicado: (2014)

Health and reproductive experiences of women with an FMR1 premutation with and without fragile X premature ovarian insufficiency
por: Wheeler, Anne C., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qh97qeucsql03ubcqs1ll7pvt7