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Ptpn20 deletion in H-Tx rats enhances phosphorylation of the NKCC1 cotransporter in the choroid plexus: an evidence of genetic risk for hydrocephalus in an experimental study

BACKGROUND: Congenital hydrocephalus occurs with some inheritable characteristics, but the mechanisms of its development remain poorly understood. Animal models provide the opportunity to identify potential genetic causes in this condition. The Hydrocephalus-Texas (H-Tx) rat strain is one of the mos...

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Detalles Bibliográficos
Autores principales: Xu, Hanbing, Miyajima, Masakazu, Nakajima, Madoka, Ogino, Ikuko, Kawamura, Kaito, Akiba, Chihiro, Kamohara, Chihiro, Sakamoto, Koichiro, Karagiozov, Kostadin, Nakamura, Eri, Tada, Nobuhiro, Arai, Hajime, Kondo, Akihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164390/
https://www.ncbi.nlm.nih.gov/pubmed/35658898
http://dx.doi.org/10.1186/s12987-022-00341-z