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Abplatin((IV)) inhibited tumor growth on a patient derived cancer model of hepatocellular carcinoma and its comparative multi-omics study with cisplatin

BACKGROUND: Cisplatin, the alkylating agent of platinum(II) (Pt(II)), is the most common antitumor drug in clinic; however, it has many side effects, therefore it is higly desired to develop low toxicity platinum(IV) (Pt(IV)) drugs. Multi-omics analysis, as a powerful tool, has been frequently emplo...

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Detalles Bibliográficos
Autores principales: Li, Xing, Zhang, Lingpu, Li, Tuo, Li, Shumu, Wu, Wenjing, Zhao, Lingyu, Xie, Peng, Yang, Jinqi, Li, Peipei, Zhang, Yangyang, Xiao, Haihua, Yu, Yingjie, Zhao, Zhenwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164404/
https://www.ncbi.nlm.nih.gov/pubmed/35659243
http://dx.doi.org/10.1186/s12951-022-01465-y