DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation

BACKGROUND: Neuropathic pain is a common and severely disabling state that affects millions of people worldwide. Microglial activation in the spinal cord plays a critical role in the pathogenesis of neuropathic pain. However, the mechanisms underlying spinal microglial activation during neuropathic...

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Detalles Bibliográficos
Autores principales: Zhang, Long-Qing, Gao, Shao-Jie, Sun, Jia, Li, Dan-Yang, Wu, Jia-Yi, Song, Fan-He, Liu, Dai-Qiang, Zhou, Ya-Qun, Mei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164405/
https://www.ncbi.nlm.nih.gov/pubmed/35658977
http://dx.doi.org/10.1186/s12974-022-02495-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164405/
https://www.ncbi.nlm.nih.gov/pubmed/35658977
http://dx.doi.org/10.1186/s12974-022-02495-x

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