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Frameshift and wild-type proteins are often highly similar because the genetic code and genomes were optimized for frameshift tolerance
Frameshift mutations have been considered of significant importance for the molecular evolution of proteins and their coding genes, while frameshift protein sequences encoded in the alternative reading frames of coding genes have been considered to be meaningless. However, functional frameshifts hav...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164415/ https://www.ncbi.nlm.nih.gov/pubmed/35655139 http://dx.doi.org/10.1186/s12864-022-08435-6 |