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Bayesian analysis of dynamic phosphoproteomic data identifies protein kinases mediating GPCR responses
BACKGROUND: A major goal in the discovery of cellular signaling networks is to identify regulated phosphorylation sites (“phosphosites”) and map them to the responsible protein kinases. The V2 vasopressin receptor is a G-protein coupled receptor (GPCR) that is responsible for regulation of renal wat...
Autores principales: | Leo, Kirby T., Chou, Chung-Lin, Yang, Chin-Rang, Park, Euijung, Raghuram, Viswanathan, Knepper, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164474/ https://www.ncbi.nlm.nih.gov/pubmed/35659261 http://dx.doi.org/10.1186/s12964-022-00892-6 |
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