Implicating effector genes at COVID-19 GWAS loci using promoter-focused Capture-C in disease-relevant immune cell types

BACKGROUND: SARS-CoV-2 infection results in a broad spectrum of COVID-19 disease, from mild or no symptoms to hospitalization and death. COVID-19 disease severity has been associated with some pre-existing conditions and the magnitude of the adaptive immune response to SARS-CoV-2, and a recent genom...

Descripción completa

Detalles Bibliográficos
Autores principales: Pahl, Matthew C., Le Coz, Carole, Su, Chun, Sharma, Prabhat, Thomas, Rajan M., Pippin, James A., Cruz Cabrera, Emylette, Johnson, Matthew E., Leonard, Michelle E., Lu, Sumei, Chesi, Alessandra, Sullivan, Kathleen E., Romberg, Neil, Grant, Struan F. A., Wells, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164584/
https://www.ncbi.nlm.nih.gov/pubmed/35659055
http://dx.doi.org/10.1186/s13059-022-02691-1

Ejemplares similares

Ejemplares similares