SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022

German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases’ proportions (2.3% for both lineages) seemed lower than...

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Autores principales: Sievers, Claudia, Zacher, Benedikt, Ullrich, Alexander, Huska, Matthew, Fuchs, Stephan, Buda, Silke, Haas, Walter, Diercke, Michaela, an der Heiden, Matthias, Kröger, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164675/
https://www.ncbi.nlm.nih.gov/pubmed/35656831
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.22.2200396
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author Sievers, Claudia
Zacher, Benedikt
Ullrich, Alexander
Huska, Matthew
Fuchs, Stephan
Buda, Silke
Haas, Walter
Diercke, Michaela
an der Heiden, Matthias
Kröger, Stefan
author_facet Sievers, Claudia
Zacher, Benedikt
Ullrich, Alexander
Huska, Matthew
Fuchs, Stephan
Buda, Silke
Haas, Walter
Diercke, Michaela
an der Heiden, Matthias
Kröger, Stefan
author_sort Sievers, Claudia
collection PubMed
description German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases’ proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease.
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spelling pubmed-91646752022-06-14 SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022 Sievers, Claudia Zacher, Benedikt Ullrich, Alexander Huska, Matthew Fuchs, Stephan Buda, Silke Haas, Walter Diercke, Michaela an der Heiden, Matthias Kröger, Stefan Euro Surveill Rapid Communication German national surveillance data analysis shows that hospitalisation odds associated with Omicron lineage BA.1 or BA.2 infections are up to 80% lower than with Delta infection, primarily in ≥ 35-year-olds. Hospitalised vaccinated Omicron cases’ proportions (2.3% for both lineages) seemed lower than those of the unvaccinated (4.4% for both lineages). Independent of vaccination status, the hospitalisation frequency among cases with Delta seemed nearly threefold higher (8.3%) than with Omicron (3.0% for both lineages), suggesting that Omicron inherently causes less severe disease. European Centre for Disease Prevention and Control (ECDC) 2022-06-02 /pmc/articles/PMC9164675/ /pubmed/35656831 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.22.2200396 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Sievers, Claudia
Zacher, Benedikt
Ullrich, Alexander
Huska, Matthew
Fuchs, Stephan
Buda, Silke
Haas, Walter
Diercke, Michaela
an der Heiden, Matthias
Kröger, Stefan
SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022
title SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022
title_full SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022
title_fullStr SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022
title_full_unstemmed SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022
title_short SARS-CoV-2 Omicron variants BA.1 and BA.2 both show similarly reduced disease severity of COVID-19 compared to Delta, Germany, 2021 to 2022
title_sort sars-cov-2 omicron variants ba.1 and ba.2 both show similarly reduced disease severity of covid-19 compared to delta, germany, 2021 to 2022
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164675/
https://www.ncbi.nlm.nih.gov/pubmed/35656831
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.22.2200396
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