ATRT-10. Single-cell transcriptional profiling of ATRTs reveals heterogeneous signatures of tumor and non-malignant cell populations

Atypical Teratoid/Rhabdoid Tumors (ATRTs) are known for exhibiting high inter-tumor heterogeneity, even though they are almost all characterized by a common loss of SMARCB1 (or rarely SMARCA4). Three subgroups have been identified at bulk methylome and transcriptome level: ATRT-TYR, ATRT-SHH, and AT...

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Detalles Bibliográficos
Autores principales: Blanco-Carmona, Enrique, Büllesbach, Annette, Federico, Aniello, Liu, Ilon, Young, Matthew D, Kildisuite, Gerda, Behjati, Sam, Vibhakar, Rajeev, Donson, Andrew, Foreman, Nicholas, Hovestadt, Volker, Shaw, McKenzie, Chi, Susan, Frühwald, Michael, Drost, Jarno, Korshunov, Andrey, Hasselblatt, Martin, Pfister, Stefan M, Jäger, Natalie, Johann, Pascal, Filbin, Mariella, Kool, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Atypical Teratoid Rhabdoid Tumor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164679/
http://dx.doi.org/10.1093/neuonc/noac079.009

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