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PATH-05 Challenge and clinical relevance of a non-matching classifier output in genome-wide DNA methylation analysis for CNS neoplasms in pediatric and adolescent patients

OBJECTIVE: The molecular classification of CNS tumors has revolutionized our understanding of the biological heterogeneity and diversity of tumor subtypes. DNA methylation-based classification allows to discriminate subtypes. Although DNA methylation-based classification can diagnose tumors with hig...

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Detalles Bibliográficos
Autores principales: Drexler, Richard, Eckhardt, Alicia, Bode, Helena, Lamszus, Katrin, Westphal, Manfred, Schüller, Ulrich, Mohme, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164687/
http://dx.doi.org/10.1093/neuonc/noac079.589