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PATH-05 Challenge and clinical relevance of a non-matching classifier output in genome-wide DNA methylation analysis for CNS neoplasms in pediatric and adolescent patients
OBJECTIVE: The molecular classification of CNS tumors has revolutionized our understanding of the biological heterogeneity and diversity of tumor subtypes. DNA methylation-based classification allows to discriminate subtypes. Although DNA methylation-based classification can diagnose tumors with hig...
Autores principales: | Drexler, Richard, Eckhardt, Alicia, Bode, Helena, Lamszus, Katrin, Westphal, Manfred, Schüller, Ulrich, Mohme, Malte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164687/ http://dx.doi.org/10.1093/neuonc/noac079.589 |
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