LGG-47. Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity During Malignant Progression in Glioma

Myeloid cells and macrophages have been shown to promote immunosuppression in high-grade gliomas (HGG), however their roles in malignant progression of low-grade glioma (LGG) are poorly understood. Here, we investigated the heterogeneity of the immune microenvironment during glioma progression using...

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Detalles Bibliográficos
Autores principales: Rajendran, Sakthi, Peterson, Clayton, Canella, Alessandro, Hu, Yang, Gross, Amy, Cam, Maren, Serin-Harmanci, Akdes, Distefano, Rosario, Nigita, Giovanni, Wang, Wesley, Hester, Mark, Miller, Katherine, Elemento, Olivier, Roberts, Ryan, Holland, Eric, Rao, Ganesh, Mardis, Elaine, Rajappa, Prajwal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Low Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164692/
http://dx.doi.org/10.1093/neuonc/noac079.359

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