HGG-15. Generation of a novel mouse model for brain tumors of the DNA methylation class “GBM MYCN”

Multiple recent publications have described a highly aggressive subgroup of pediatric glioblastoma, which is clearly separable from other pediatric and adult glioblastoma based on its DNA methylation profile (GBM MYCN). These tumors almost exclusively occur in children and have a median overall surv...

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Detalles Bibliográficos
Autores principales: Schoof, Melanie, Godbole, Shweta, Walter, Carolin, Dottermusch, Matthias, Albert, Thomas, Ballast, Annika, Göbel, Carolin, Neyazi, Sina, Holdhof, Dörthe, Kresbach, Catena, Blattner-Johnson, Mirjam, Modemann, Franziska, Afflerbach, Ann-Kristin, Eckhardt, Alicia, Struve, Nina, Jones, David, Kerl, Kornelius, Neumann, Julia E, Schüller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164702/
http://dx.doi.org/10.1093/neuonc/noac079.230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164702/
http://dx.doi.org/10.1093/neuonc/noac079.230

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