MEDB-18. Elongation control of mRNA translation supports Group 3 medulloblastoma adaptation to nutrient deprivation

Group 3 affiliation and MYC genetic amplification are associated with poor life expectancy and substantial morbidity in children suffering from medulloblastoma (MB). However, the high metabolic demand induced by MYC-driven transformation sensitizes MYC-overexpressing MB to cell death under condition...

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Detalles Bibliográficos
Autores principales: Delaidelli, Alberto, Yao, Betty, Wang, Que Xi, Huang, Yue Zhou, Negri, Gian Luca, Hughes, Christopher, Zhang, Haifeng, Leprivier, Gabriel, Sorensen, Poul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Medulloblastoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164713/
http://dx.doi.org/10.1093/neuonc/noac079.393

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