HGG-50. Specific sensitivity of pediatric high-grade glioma with ATRX inactivation to PARP inhibitor combinations

Pediatric high-grade gliomas (pHGG) account for approximately 12% of pediatric brain tumors. Despite advances in molecular diagnosis and identification of discrete molecular subtypes, pHGG are the leading cause of cancer-related death in children. Thus, current research focuses on identifying novel...

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Detalles Bibliográficos
Autores principales: Laemmerer, Anna, Kirchhofer, Dominik, Madlener, Sibylle, Loetsch-Gojo, Daniela, Jaunecker, Carola N, Gabler, Lisa, Mayr, Lisa, Stepien, Natalia, Baumgartner, Alicia, Dieckmann, Karin, Pfister, Stefan M, Kool, Marcel, Krausert, Sonja, Gopisetty, Apurva, Jäger, Natalie, Peyrl, Andreas, Azizi, Amedeo A, Berger, Walter, Gojo, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164730/
http://dx.doi.org/10.1093/neuonc/noac079.265

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