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DIPG-09. Diffuse Midline Glioma-Adaptive Combinatory Trial (DMG-ACT): A biology-driven platform trial in pediatric and young adult patients with diffuse midline glioma

BACKGROUND: Despite advances in our understanding of the biology of diffuse midline gliomas (DMGs), little progress has been made in improving outcomes. Therapy development is limited by lack of preclinical data across multiple model systems and laboratories; limited knowledge about blood-brain barr...

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Detalles Bibliográficos
Autores principales: Franson, Andrea, Kline, Cassie, Molinaro, Annette, Zhang, Yalan, Hitchner, Kelly, Koschmann, Carl, Nazarian, Javad, Mueller, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164735/
http://dx.doi.org/10.1093/neuonc/noac079.066

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