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DIPG-56. Development and application of a novel antibody against CD99 as a therapeutic strategy in Diffuse Midline Glioma

BACKGROUND: There is an unmet need to identify novel targeted therapies for Diffuse Midline glioma (DMG) which is currently a refractory disease. Recently, we identified high expression of a cell surface antigen, CD99 in H3K27M-mutant expressing DMGs compared to other normal brain counterparts. We d...

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Detalles Bibliográficos
Autores principales: Venkataraman, Sujatha, Balakrishnan, Ilango, Madhavan, krishna, Chetty, Senthilnath Lakshmana, Pierce, Angela, Fosmire, Susan, Nuss, Zachary, Coleman, Philip, Green, Adam, Vibhakar, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164746/
http://dx.doi.org/10.1093/neuonc/noac079.113