LGG-17. Preventing recurrence: targeting molecular mechanisms driving tumor growth rebound after MAPKi withdrawal in pediatric low-grade glioma

Pediatric low-grade gliomas, a diverse group of WHO grade 1 and 2 glial or glioneural tumors, comprise the most common category of primary brain tumors in children. The majority of these tumors are driven by alterations in the MAPK pathway, making them in principle susceptible to MAPKi therapy. Whil...

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Detalles Bibliográficos
Autores principales: Kocher, Daniela, Selt, Florian, Valinciute, Gintvile, Zaman, Julia, Vonhören, David, Pusch, Stefan, Guiho, Romain, Martinez-Barbera, Juan Pedro, von Deimling, Andreas, Pfister, Stefan M, Jones, David T W, Brummer, Tilman, Witt, Olaf, Milde, Till, Sigaud, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Low Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164816/
http://dx.doi.org/10.1093/neuonc/noac079.332

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