HGG-42. Evolutionary selection of key oncogenic alterations in patient-derived models of paediatric diffuse high grade glioma (PDHGG) subtypesin vitro andin vivo

PDHGG are a diverse group of childhood brain tumours comprising multiple subgroups carrying distinct molecular drivers. Patient-derived models accurately recapitulating this underlying biology are critical for mechanistic/preclinical studies aimed at improving patient outcome, however their behaviou...

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Detalles Bibliográficos
Autores principales: Mackay, Alan, Temelso, Sara, Carvalho, Diana, Kessler, Ketty, Boult, Jessica, Izquierdo, Elisa, Pereira, Rita, Potente, Elisabet Fernandez, Burford, Anna, Molinari, Valeria, Bjerke, Lynn, Grabovska, Yura, Rogers, Rebecca, Crampsie, Shauna, Das, Molina, Robinson, Simon, Clarke, Matthew, Jones, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
High Grade Glioma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164821/
http://dx.doi.org/10.1093/neuonc/noac079.257

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