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MODL-03. Establishment of intraventricular Shh inhibition as a therapeutic option for young patients with medulloblastoma

The prognosis of pediatric medulloblastoma is still dissatisfying today and tumor survivors often suffer from severe treatment-related morbidities. This poses an urgent need for more efficient therapies. Shh medulloblastoma is characterized by mutations in the Sonic Hedgehog (Shh) pathway, providing...

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Detalles Bibliográficos
Autores principales:	Kresbach, Catena, Schoof, Melanie, Holst, Lea, Leven, Tara, Yorgan, Timur, Wrzeszcz, Antonina, Rutkowski, Stefan, Schüller, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Preclinical Models/Experimental Therapy/Drug Discovery
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164841/ http://dx.doi.org/10.1093/neuonc/noac079.626

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