IMMU-04. Transcriptional analysis reveals distinct microenvironmental subgroups across pediatric nervous system tumors

INTRODUCTION: Recent clinical trials of immune checkpoint inhibitors indicated 5-11% response rate in pediatric patients depending on cancer type and expression of target proteins. Currently, a systematic analysis characterizing the immune microenvironment of childhood tumors is lacking. The main ob...

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Detalles Bibliográficos
Autores principales: Nabbi, Arash, Beck, Pengbo, Delaidelli, Alberto, Oldridge, Derek A, Sudhaman, Sumedha, Zhu, Kelsey, Yang, S Y Cindy, Mulder, David T, Bruce, Jeffrey P, Paulson, Joseph N, Raman, Pichai, Zhu, Yuankun, Silll, Martin, Brabetz, Sebastian, Lambo, Sander, Johann, Pascal D, Resnick, Adam C, Sorensen, Poul H, Malkin, David, Kool, Marcel, Jones, David T W, Pfister, Stefan M, Jäger, Natalie, Pugh, Trevor J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164869/
http://dx.doi.org/10.1093/neuonc/noac079.297

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