MEDB-43. Development of a bioinformatics pipeline for identification of differential DNA methylation events associated with medulloblastoma relapse

Relapsed medulloblastoma (rMB) is treatment-resistant and fatal in ~95% of cases. The epigenetic features of rMB, and any role as drivers of disease relapse/treatment-resistance have yet to be investigated. We therefore developed a pipeline to identify differentially methylated CpGs (DM-CpGs) and re...

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Detalles Bibliográficos
Autores principales: Kui, Christopher, Richardson, Stacey, Schwalbe, Edward C, Thompson, Dean, Keeling, Claire, Strathdee, Gordon, Dufour, Christelle, Bailey, Simon, Ramaswamy, Vijay, Clifford, Steven C, Hill, Rebecca M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Medulloblastoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164906/
http://dx.doi.org/10.1093/neuonc/noac079.417

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