OTHR-39. Extraneural spreading of a diffuse leptomeningeal glioneuronal tumor in a child: patient-derived models show sensitivity to vinblastin and trametinib

Diffuse leptomeningeal glioneuronal tumors (DLGNT) are rare neoplasms of the central nervous system. We describe the generation of patient-derived models from a DLGNT that metastasized to the peritoneal cavity via a ventriculoperitoneal shunt in a child. The original tumor contained a KIAA1549:BRAF...

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Detalles Bibliográficos
Autores principales: Messiaen, Julie, Claeys, Annelies, Shetty, Aniket, Spans, Lien, Derweduwe, Marleen, Uyttebroeck, Anne, Depreitere, Bart, Bempt, Isabelle Vanden, Sciot, Raf, Ligon, Keith, Jones, David, Jacobs, Sandra, De Smet, Frederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Others (Not Fitting Any Other Category)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164998/
http://dx.doi.org/10.1093/neuonc/noac079.577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9164998/
http://dx.doi.org/10.1093/neuonc/noac079.577

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