DIPG-46. Radiation induced senescence in diffuse intrinsic pontine glioma cells reveals selective vulnerability to Bcl-XL inhibition

Diffuse intrinsic pontine glioma remains a devastating condition with a dismal five year survival rate less than 5%. New approaches for treating this aggressive disease are critical to driving progress. Conventional radiotherapy remains the cornerstone of treatment, with no chemotherapeutic agent fo...

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Detalles Bibliográficos
Autores principales: Vardon, Ashley, Guiho, Romain, Carvalho, Diana, Boult, Jessica, Carter, Rebecca, Grabovska, Yura, Mackay, Alan, Zheng, Guangrong, Zhou, Daohong, Hiley, Crispin, Lythgoe, Mark, Jones, Chris, Hargrave, Darren, Martinez-, Juan-Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Diffuse Midline Glioma/DIPG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165002/
http://dx.doi.org/10.1093/neuonc/noac079.103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165002/
http://dx.doi.org/10.1093/neuonc/noac079.103

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