EPEN-02. Adaptive Convergence of Methylomes Reveals Epigenetic Drivers and Boosters of Repeated Relapses in Patient-matched Childhood Ependymomas and Identifies Targets for Anti-Recurrence Therapies

Ependymoma (EPN) is the third most common brain tumor in children and frequently recurs. Here, we report an integrated longitudinal analysis of epigenetic, genetic and tumorigenic changes in 30 patient-matched repeated relapses obtained from 10 pediatric patients to understand the mechanism of recur...

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Detalles Bibliográficos
Autores principales: Zhao, Sibo, Li, Jia, Zhang, Huiyuan, Qi, Lin, Du, Yuchen, Kogiso, Mari, Braun, Frank K, Huang, Yulun, Teo, Wan-Yee, Baxter, Patricia, Adesina, Adekunle, Song, Yongcheng, Sun, Deqiang, Li, Xiao-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Ependymoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165025/
http://dx.doi.org/10.1093/neuonc/noac079.139

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