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DDEL-05. Intraventricular therapy with topotecan is feasible and safe: Experience in 50 pediatric patients with various malignant brain tumors

BACKGROUND: Malignant brain tumors carry a high risk for leptomeningeal dissemination, but the CSF compartment is often not affected by systemic therapy. Intraventricular therapy via an Ommaya reservoir is one possibility to increase the cytotoxic drug concentration in the CSF. Unfortunately, the nu...

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Detalles Bibliográficos
Autores principales:	Peyrl, Andreas, Stepien, Natalia, Mayr, Lisa, Azizi, Amedeo, Gojo, Johannes, Baumgartner, Alicia, Hedrich, Cora, Lippolis, Maria Aliotti, Slavc, Irene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Drug Delivery/Pharmacokinetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165077/ http://dx.doi.org/10.1093/neuonc/noac079.126

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