Cargando…

THER-01. Precision brain tumor therapy by AAV-mediated oncogene editing

Pediatric high-grade glioma is a heterogeneous group of highly malignant tumors of the central nervous system, with a median overall survival of less than two years after diagnosis, demanding novel treatment options. One innovative approach is gene therapy, which has so far been hampered for cancer...

Descripción completa

Detalles Bibliográficos
Autores principales:	von Soosten, Laura, Haar, Janina, Frehtman, Veronika, Holderbach, Stefan, zu Belzen, Julius Upmeier, Jendrusch, Michael, Okonechnikov, Konstantin, Pfister, Stefan M, Grimm, Dirk, Leuchs, Barbara, Jones, David, Kutscher, Lena M, Zuckermann, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Viral/Gene Therapy and other Novel Therapies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165130/ http://dx.doi.org/10.1093/neuonc/noac079.695

Ejemplares similares

THER-01. AWAKING THE IMMUNE SYSTEM WITH AN IMMUNO-ONCOLYTIC VIRUS AS A THERAPEUTIC STRATEGY FOR DIPGs
por: Laspidea, Virginia, et al.
Publicado: (2020)

THER-04. IS THERE A ROLE FOR CANNABIDIOL IN THE TREATMENT OF CHILDHOOD BRAIN TUMOURS?
por: Lockwood, George, et al.
Publicado: (2020)

THER-07. INHIBITION OF THE RAS SIGNALING ENHANCES VIRAL ONCOLYSIS IN MALIGNANT GLIOMAS
por: Arakawa, Yoshiki, et al.
Publicado: (2020)

THER-02. Pediatric brain tumor cultures reveal differential susceptibility to four oncolytic viruses
por: Vazaios, Konstantinos, et al.
Publicado: (2022)

THER-09. ONCOLYTIC ADENOVIRUS, DNX-2401, FOR NAIVE DIFFUSE INTRINSIC PONTINE GLIOMAS: A PHASE I CLINICAL TRIAL
por: Iñigo-Marco, Ignacio, et al.
Publicado: (2020)

THER-02. EVALUATION OF THE ONCOLYTIC VIRUS DELTA24-RGD AS AN ANTI-TUMOR AGENT IN PRECLINICAL MODELS OF LOCALIZED AND DISSEMINATED AT/RT
por: Garcia-Moure, Marc, et al.
Publicado: (2020)

THER-03. IN VITRO EVALUATION OF THE EFFECT OF CANNABIDIOL ON PAEDIATRIC BRAIN TUMOUR CELL LINES USING A PULSED TREATMENT REGIME
por: Faulkes, Sophie, et al.
Publicado: (2020)

THER-05. GENETICALLY STABLE POLIOVIRUS VECTOR CARRYING H3.3K27M ANTIGEN FOR TREATMENT OF DIFFUSE MIDLINE GLIOMA BY INTRAMUSCULAR INJECTION
por: Mosaheb, Mubeen, et al.
Publicado: (2020)

THER-08. SGT53 – A NOVEL p53 NANOMEDICINE INDUCES SIGNIFICANT RESPONSES IN CHILDREN WITH RECURRENT MEDULLOBLASTOMA AND CHOROID PLEXUS CARCINOMA: A REPORT OF TWO CASES
por: Hwang, Eugene, et al.
Publicado: (2020)

THER-06. THERAPEUTIC EFFICACY OF RRV-MEDIATED PRODRUG ACTIVATOR GENE THERAPY IN CLINICAL TRIALS OF RECURRENT HIGH-GRADE GLIOMA AND IN MURINE ORTHOTOPIC MODELS OF INTRACEREBRAL GLIOMA AND INTRACEREBELLAR MEDULLOBLASTOMA
por: Richardson, Angela, et al.
Publicado: (2020)

Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis
por: Lacroix, Jeannine, et al.
Publicado: (2014)

Intrathymic AAV delivery results in therapeutic site-specific integration at TCR loci in mice
por: Calabria, Andrea, et al.
Publicado: (2023)

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage
por: Binny, Christopher, et al.
Publicado: (2012)

Pharmacokinetic analysis identifies a factor VIII immunogenicity threshold after AAV gene therapy in hemophilia A mice
por: Lundgren, Taran S., et al.
Publicado: (2022)

Triptans in clinical practice: the basic scientist’s point of view
por: Buzzi, M. Gabriella
Publicado: (2001)

Clinical experience with triptans
por: Zanchin, Giorgio, et al.
Publicado: (2001)

Triptans: the experience of a clinical pharmacologist in clinical practice
por: Pini, Luigi Alberto, et al.
Publicado: (2001)

Anticonvulsant drugs in migraine prophylaxis
por: Frediani, Fabio, et al.
Publicado: (2001)

Up to date on the use of triptans for child and adolescent migraine: state of the art
por: Calderoni, Dario, et al.
Publicado: (2001)

Menstrual migraine
por: Moschiano, Franca, et al.
Publicado: (2001)

New strategies for the treatment of migraine attacks
por: Genco, Sergio, et al.
Publicado: (2001)

Diagnostic and therapeutic guidelines for migraine. Italian Society for the Study of Headaches (SISC)
por: Gallai, Virgilio, et al.
Publicado: (2001)

Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?
por: Raffaello, Wilson Matthew, et al.
Publicado: (2021)

Rationale for and Practical Use of Sacubitril/Valsartan in the Patient’s Journey with Heart Failure and Reduced Ejection Fraction
por: Gori, Mauro, et al.
Publicado: (2021)

Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids
por: Fenton, Chloe, et al.
Publicado: (2021)

How to Implant His Bundle and Left Bundle Pacing Leads: Tips and Pearls
por: Ponnusamy, Shunmuga Sundaram, et al.
Publicado: (2021)

Extracorporeal Membrane Oxygenation as a Treatment for Branch Pulmonary Artery Rupture Following Right Heart Catheterisation
por: Agrawal, Vineet, et al.
Publicado: (2022)

Cell Therapy in Heart Failure with Preserved Ejection Fraction
por: Frljak, Sabina, et al.
Publicado: (2022)

Endpoints in Heart Failure Drug Development
por: Hussain, Aliza, et al.
Publicado: (2022)

Management of Type 2 Diabetes in Stage C Heart Failure with Reduced Ejection Fraction
por: Agarwalla, Anjali, et al.
Publicado: (2022)

Systemic antibiotic therapy as an adjunct to non‐surgical peri‐implantitis treatment: A single‐blind RCT
por: De Waal, Yvonne C. M., et al.
Publicado: (2021)

Medical Treatment of Heart Failure with Reduced Ejection Fraction in the Elderly
por: Milinković, Ivan, et al.
Publicado: (2022)

Soft tissue phenotype modification predicts gingival margin long‐term (10‐year) stability: Longitudinal analysis of six randomized clinical trials
por: Barootchi, Shayan, et al.
Publicado: (2022)

Evidence and risk indicators of non‐random sampling in clinical trials in implant dentistry: A systematic appraisal
por: Shi, Jun‐Yu, et al.
Publicado: (2021)

Pocket closure and residual pockets after non‐surgical periodontal therapy: A systematic review and meta‐analysis
por: Citterio, Filippo, et al.
Publicado: (2021)

The microbiome of dental and peri‐implant subgingival plaque during peri‐implant mucositis therapy: A randomized clinical trial
por: Philip, Juliana, et al.
Publicado: (2021)

The efficacy of the adjunct use of subgingival air‐polishing therapy with erythritol powder compared to conventional debridement alone during initial non‐surgical periodontal therapy
por: Divnic‐Resnik, Tihana, et al.
Publicado: (2022)

A person‐centred, theory‐based, behavioural intervention programme for improved oral hygiene in adolescents: A randomized clinical field study
por: Dimenäs, Sandra L., et al.
Publicado: (2022)

Two short implants versus one short implant with a cantilever: 5‐Year results of a randomized clinical trial
por: Thoma, Daniel S., et al.
Publicado: (2021)

The effect of omega‐3 fatty acids on active periodontal therapy: A systematic review and meta‐analysis
por: Van Ravensteijn, Myrlon M., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a575kddcvurhj0a8auvteujpo4